Ethereum Soars Over 20% in a Day — What Altcoins Should You Watch Next?

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In a dramatic turn of events, Ethereum (ETH) surged over 20% in a single day on May 20, 2025, reigniting excitement across the crypto market. This sharp rally followed reports that the U.S. Securities and Exchange Commission (SEC) had requested several institutions to accelerate updates to their 19b-4 filings—documents directly tied to the approval process for spot Ethereum ETFs.

This unexpected regulatory momentum not only boosted ETH but also triggered strong gains across major Ethereum-based altcoins: Lido (LDO) rose 20.1%, Optimism (OP) climbed 15%, Arbitrum (ARB) gained 16.7%, Uniswap (UNI) jumped 19.5%, and ENS surged 19.3%. The ripple effect was immediate and powerful.

According to Bloomberg Intelligence, VanEck’s spot Ethereum ETF is set for a final decision on May 23, with Ark Invest and 21Shares following closely on May 24. These dates are now critical inflection points for the entire cryptocurrency ecosystem.

👉 Discover how ETF developments could reshape your crypto strategy in 2025.

What’s Driving the Ethereum Rally?

The core catalyst behind ETH’s surge is clear: spot ETF anticipation. While Bitcoin ETFs have already launched successfully, an approved Ethereum ETF would represent the next major milestone in institutional crypto adoption.

Analysts at QCP Capital suggest that if approvals come through, ETH could quickly approach $4,000, with a potential rise to $5,000 later this year. Conversely, rejection might push prices back toward $3,000—but even then, sentiment remains cautiously optimistic. Why? Because the regulatory environment has clearly shifted. Approval isn’t just possible anymore; it feels inevitable.

Historically, ETH has underperformed BTC throughout much of 2024, leading some investors to question whether a traditional "altseason" will occur. But this sudden momentum shift suggests we may be entering a new phase—one where Ethereum leads the charge.

Is Altseason Finally Approaching?

Past bull markets followed a predictable pattern:

  1. Bitcoin rises
  2. Ethereum follows
  3. Large-cap altcoins gain traction
  4. Mid- and low-cap projects surge
  5. Meme coins explode

However, 2025 is rewriting that script. Meme coins like PEPE made early moves, breaking the traditional sequence. Yet recent capital flows show renewed interest returning to ETH and high-fundamental projects—another positive signal.

Still, caution is warranted. A report from Binance highlights a looming supply overhang: approximately $155 billion in new tokens could unlock between 2024 and 2030. Without proportional demand growth, this influx may create significant selling pressure.

That said, Ethereum’s role as the “king of altcoins” positions it uniquely. Its performance often sets the tone for broader altcoin strength—especially within its own ecosystem.

Key Metrics to Watch

One important indicator is Total3, which measures the total market cap of all cryptocurrencies excluding Bitcoin and Ethereum. At the time of writing, Total3 sits at $699 billion**. If it stabilizes above **$700 billion, that could signal strong altseason momentum building.

Additionally, upcoming mainnet launches of major protocols—such as Blast (June 26), zkSync, LayerZero, and EigenLayer—are likely timed to coincide with favorable market conditions. These events can act as powerful catalysts for specific sectors and drive speculative interest.

How to Approach Altcoin Research in 2025

Rather than chasing hype or relying on direct recommendations, focus on frameworks and narratives shaping the current cycle. The following altcoins represent promising opportunities across key themes like AI, RWA, DePIN, GameFi, Layer2, and Restaking.

These selections are not investment advice, but rather starting points for deeper research based on technological merit, community strength, and macro trends.

1. Mantle (MNT) – Layer2

Mantle is a DAO-governed ecosystem anchored by Mantle Network—a modular, EVM-compatible Layer2 solution. By combining Rollup technology with decentralized data availability layers, it inherits Ethereum’s security while reducing transaction costs significantly.

Its unique architecture separates execution, settlement, consensus, and data availability into distinct layers—offering scalability without sacrificing decentralization.

2. Pendle (PENDLE) – Restaking

Pendle enables users to tokenize future yield from interest-bearing assets like staked ETH or liquidity positions. Users can sell this yield forward for upfront capital or buy discounted future yields—effectively creating a marketplace for predictable returns.

This innovative model enhances capital efficiency during both bull and bear markets.

3. AltLayer (ALT) – Zero Knowledge Proofs & RaaS

AltLayer offers “instant finality” rollups-as-a-service, allowing developers to deploy customized optimistic rollups secured by Ethereum or other L1s/L2s. Each rollup is application-specific, enabling high-performance dApps without compromising security.

It’s a foundational infrastructure play in the modular blockchain era.

4. Ondo (ONDO) – Real World Assets (RWA)

Ondo brings institutional-grade finance on-chain, partnering with BlackRock to offer tokenized U.S. Treasury and bond funds. Users earn yield on USDC by gaining exposure to real-world credit instruments—all transparently recorded on-chain.

With growing institutional interest in RWA, Ondo stands at the forefront of this convergence.

5. Maple (MPL) – RWA

Maple provides unsecured corporate loans to institutions via decentralized credit markets. Lenders earn yield while borrowers access capital efficiently. MPL governs risk parameters and protocol upgrades.

It’s redefining how traditional finance interacts with DeFi.

6. Centrifuge (CFG) – RWA

Centrifuge connects DeFi with real-world assets like invoices, royalties, and receivables. SMEs gain cheaper funding; investors receive stable yields. CFG tokens are used for governance, staking, and transaction fees within the network.

A long-standing leader in asset tokenization.

7. Aleph.im (ALEPH) – DePIN

Aleph.im is a decentralized cloud computing platform offering serverless computing, file storage, and indexing—similar to Firebase but fully decentralized. It supports AI models, DeFi analytics, and cross-chain messaging.

Ideal for developers aiming to fully decentralize their app stacks.

8. Oraichain (ORAI) – AI & Layer1

Oraichain integrates AI into blockchain through AI-powered oracles, smart contracts, NFTs, and GameFi applications. Its AI oracle delivers verified machine learning predictions to smart contracts—enabling smarter automation across Web3.

A pioneer in merging artificial intelligence with decentralized systems.

9. Pepe (PEPE) – Memes

Born as a tribute to the iconic Pepe the Frog meme, PEPE captured cultural attention early in the bull run. While highly speculative, memecoins often serve as liquidity drivers during altseasons due to viral adoption and trader enthusiasm.

High risk, high volatility—but historically part of the cycle.

10. Heroes of Mavia (MAVIA) – GameFi

Mavia is a AAA mobile strategy game similar to Clash of Clans or Rise of Kingdoms. Players build bases, train troops, and battle others—all while earning MAVIA tokens through gameplay and land ownership.

GameFi continues to attract mainstream attention as blockchain gaming matures.

Note: Projects #11–20 will be published separately via supplementary research channels.

👉 Explore tools and insights that help identify the next breakout altcoins before they trend.

Frequently Asked Questions (FAQ)

Q: Will a spot Ethereum ETF definitely be approved?
A: While nothing is guaranteed, regulatory signals are stronger than ever. Even if delayed or rejected initially, most experts believe approval is likely within 2025 due to growing institutional demand and political shifts.

Q: Does ETH’s rally guarantee an altseason?
A: Not automatically—but it increases probability. Sustained ETH strength and rising Total3 values are key indicators to confirm broader altcoin momentum.

Q: Are memecoins safe investments?
A: Memecoins like PEPE carry extremely high risk due to lack of fundamentals and extreme volatility. They should only represent a small portion of speculative portfolios—if any.

Q: How should beginners approach altcoin investing?
A: Focus on dollar-cost averaging (DCA), prioritize projects with strong use cases and active development teams, and avoid chasing short-term pumps driven by hype alone.

Q: What happens when large token unlocks occur?
A: Massive supply releases can cause downward pressure if demand doesn’t match. Always check vesting schedules and team allocations before investing in newer projects.

Q: Is now too late to enter the market?
A: Timing the top or bottom is nearly impossible. Instead of trying to predict peaks, focus on long-term trends and consistent accumulation strategies like DCA.


While short-term price action grabs headlines, lasting gains come from understanding narratives, cycles, and structural shifts in the market.

👉 Stay ahead of the next market wave with real-time data and expert analysis tools.